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Bulk Drug Manufacturing

SPICA Laboratories to set up bulk drug unit at Nalagonda


SPICA Laboratories to set up bulk drug unit at Village S. Lingotma, Mandal Choutuppal in Nalagonda district of Andhra Pradesh with an investment of Rs. 4.16 million. The company will manufacture any of the following 23 products and 3 –by product at the plant.

S.N.

Products

Production Capacity (TPA)

Main products :

1

Tramadol Hydrochloride

120.0

2

Carvedilol

48.0

3

Ezetimibe

12.0

4

Montelukast Sodium

12.0

5

Rabeprazole Sodum

36.0

6

Modafinil

12.0

7

Tamsulosin Hydrochloride

12.0

8

Moxifloxacin Hydrochloride Monohydrate

48.0

9

Quetiapine Hemifumarate

48.0

10

Nimesulide

120.0

11

Lamotrigine

60.0

12

Dobutamine Hydrochloride

12.0

By-products :

13

Trimethyl Silyl alcohol

3.348

14

Hydrogen Bromide

36.0

15

Alpha Pinene

11.04

Zyfine to set up bulk drug unit at Sanand


 

Zyfine, a unit of Cadila Health Care Limited-Fine Chemical Division is to set up  bulk drug unit at Changodhar Sarkhej-Bavla Highway, Sanand in Ahmedabad district of Gujarat. It will be a R&D unit engaged in manufacturing of  fine chemicals and its intermediates with production capacity of 500kg/m. It is proposed to increase the capacity of fine chemicals and intermediates to 3405 kg/month. The total project cost is estimated at Rs. 220 million and will produce the following bulk drugs.

Sl.No

Name of Proposed Product

Proposed Capacity Kg/Month

 

Bulk Drugs & Fine Chemicals

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

                3405

1.     

4-hydroxy-2 (N ? methyl) - 2H ? thieno [2, 3 ? e] 1, 2 ? hiazine 3 ? carboxylic methyl ester 1,1 ? dioxide) (TNX)

2.     

 5-amino ? 2, 1, 3 ? benzothiadizole (BTA)

3.     

 5 ? Hydrazino ? 2 ? methoxypyridine dihydrochloride (MHPH)

4.     

Tetrakis (1 ? isonitrilo ? 2 ? methoxy ? 2 ? methyl propane) copper (I) tetrafluoroborate complex [Copper MIBI Complex]

5.     

 3,4 ? Dihydroxy ? 5 ? Nitrobenzaldehyde (DNB)

6.     

N ? Amino ? 2 ? methylindoline ? p - toluenesulfonate (AMI)

7.     

4 ? Chloro ? 3 ? sulfamoylbenzoyl chloride (CSBC)

8.     

(S) ? 3 ? {5 - (4 ? flurophenyl) ? 5 ? oxopentanoyl ? 4 ? phenyloxazolidin ? 2 ? on} (EVA ? KIT)

9.     

2 - (4 ? benzyloxyphenyl) ethyl methylamine Hydrochloride  (BPA)

10.               

1 ? cyclopropyl ? piperidin ? 4 ? ylamine (CPP)

11.               

N ? isopropyl ? 4 ? aminopiperidine (IPP)

12.               

DL 2,6 ? Pipecolicxylidide (RPV)

13.               

6 ? Methoxy ? 2 ? methyl ? 3 ? pyridineacetonitrile (MMP)

14.               

GEMIFLXACINE (GMFC)

15.               

Sucraloze (SUR)

16.               

Ciclesonide (CIC)

17.               

Exemestane

18.               

Anastrozole

19.               

Letrozole

20.               

Bicalutamide

21.               

Bortezumib

22.               

Budesonide

23.               

Capeatabine

24.               

Carboplatin

25.               

Cyclosporin

26.               

Docetaxel

27.               

Erlotinib

28.               

Fluticasone

29.               

Lenalidomide

30.               

Oxaliplatin

31.               

Pemetrexed

32.               

Temozolomide

33.               

Vorinostat

34.               

Gefitinib

35.               

Gemcitabine

36.               

Imatinib

37.               

Irinotecan

TOTAL

               3405

Cipla to set up 320 MT Bulk Drug and 2000 MNA Formulation Unit at Kurkhumbh


Cipla to set up 320 MT Bulk Drug and 2000 MNA (million number per year)  Formulation Unit at Kurkhumbh in Daund in Pune district of Maharashtra.  Six number of products in the categories of Anti-retroviral, Anti-inflammatory, Antidiabetic, Anti-bacterial, Anti-psychotic, Antihypertensive, with total manufacturing capacity of 320 MT/Year will be produced. The total project cost is estimated at Rs. 3840 million.

Inga Pharmaceuticals to set up bulk drug unit at Ambernath


Inga Pharmaceuticals to set up bulk drug unit with a capacity of 5.15 mtm at Ambernath in Thane district of Maharashtra with an investment of Rs. 45 million.

 The products are Phytochemicals and will be extracted from natural sources. The company plans to produce the following drugs from the new unit

S.No.

Name of Product

Quantity

(kg/Month)

1

Belladonna Dry Extract

200

2

Belladonna Soft Extract (BSE)

200

3

Berberine Hydrochloride (BEH)

200

4

Berberine Sulphate (BES)

200

5

Berberine Tannate (BET)

200

6

Caffeine Citrate (CC)

500

7

Calcium Sennosides (CS)

500

8

Methoxsalen (MM)

10

9

Noscapine (NH)

500

10

Noscapine Hydrochloride (NHH)

100

11

Papaverine Hydrochloride (PAH)

200

12

Podophyllum Resin (PR)

100

13

Podophyllotoxin (PT)

5

14

Powered Rauwolfia Serpentina (RS)

100

15

Prepared Ergot (PE)

500

16

Psyllium Husk Power (PHP)

500

17

Quinidine Sulphate (QDS)

25

18

Quinine Dihydrochloride (QHH)

100

19

Quinine Hydrochloride (QH)

100

20

Quinin Sulphate (QS)

500

21

Total Alkaloids of Belladonna (TAB)

5

22

Tetra-Hydro Papaverine Hydrochloride (THPH)

200

23

Dopamine Hydrochloride (DPH)

200

Total

5145

 

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