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Ausha P & C Industries to set up bulk drug unit at Ankleshwar in Bharuch


Ausha P & C Industries to set up bulk drug unit at Ankleshwar in Bharuch in Gujarat with an investment of Rs. 5.0 million. The expansion details of the new unit are as follows.

Sr. No.

Product Name

Capacity in MT/month

1

7-Amino-3-(1-methyl-1-pyrolidinio)-methyl-ceph-3-em-4carboxylate (by two alternate processes)

5.0 MT / month of any one individual product or combined production of all 24 products

2

Cefepime dihydrochloride monohydrate(Nonsterile) (by two alternate processes)

3

3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine Hydrochloride (by two alternate processes)

4

3,4-dimethoxy-N-[3-(4-methoxyphenyl)-1-methylpropyl]-B-phenylethylamine hydrochloride (by two alternate processes)

5

5-chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone technical

6

4-[1-oxo-4-[4-(hydroxy diphenylmethyl)-1-piperidinyl] butyl] alpha, alpha-dimethyl benzene acetic acid (by two alternate processes)

7

4-[1-hydroxy-4-[4-hydroxy diphenylmethyl)-1 -piperidinyl] butyl] alpha, alpha-dimethyl benzene acetic acid (by two alternate processes)

8

5-methoxyparatrifluoro methyl valerophenone (by two alternate processes)

9

5-methoxy-4`-(trifluoro methyl)valerophenone-[E]   -O-(2-aminoethyl)-oxime (by two alternate processes)

10

2-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridine-2-yl methylthio] benzimidazole

11

2-hydroxymethyl-3-methyl- 4-(2,2,2-trifluoroethoxy) pyridine

12

4-(1,2,4-triazol-1-yl methyl)-benzonitrile

13

4-4`-(1H-1,2,4-triazol-1-yl methylene)-bis[benzonitrile]

14

1-[N2-(1-carboxy-3-phenyl propyl)-N6-(tert-butoxy carbonyl)L-lysyl)-L-proline

15

1,2,3,9-tetrahydro-9-methyl -3-[(2-methyl-1H-  imidazol-1-yl)methyl]-4H-carbazol-4-one

16

2-dimethylaminomethyl cyclohexanone hydrochloride

17

2-[(dimethylamino)methyl]    -1-(3-methoxyphenyl) cyclohexanol

18

4-(5-methyl-3-phenyl-4-isoxazolyl)-benzene sulfonamide

19

N,N,6-Trimethyl-2-(4-methyl phenyl)-imidazo[1,2-a] pyridine-3 acetamide

20

2-(4-methyl phenyl)-6- methylimidazo[1,2-a] pyridine-3 acetonitrile

21

7-Amino-3-vinylcephalosporanic Acid

22

Dibenzo [b,f] [1,4] thiazepine-(10H)-11-one

23

3,3-dimethyl-7-oxo-4-thio-1-azabiclo[3,2,0] heptane-2-carboxylic acid-4,4-dioxide

24

2-(1-piperazinylethoxy) ethanol

 

Cardkem Pharma to expand its bulk drug unit at Ankleshwar in Gujarat


Cardkem Pharma to expand its bulk drug unit at Ankleshwar in Bharuch district of Gujarat  with an investment of Rs. 10 million.

Sr

 

Product

Production capacity in MT/month

Existing

Proposed

Total

1

PYRIDINE HYDROBROMIDE

200.000

--

200.000

2

PHENYL ACETIC ACID

3.000

--

3.000

3

PHOSPHOROUS TRIBROMIDE

20.000

--

20.000

4

ACETYL BROMIDE

5.000

--

5.000

5

PROPIONYL BROMIDE

5.000

--

5.000

6

TRI PHENYL PHOSPHENE

9.000

--

9.000

7

ETHYL TRIPHENYL PHOSPHONIUM BROMIDE

5.000

--

5.000

8

PYRIDINIUM BROMIDE PERBROMIDE

5.000

--

5.000

9

4 HYDROXY CARBAZOLE

6.000

--

6.000

10

N METHYL CARBAZALONE

2.000

--

2.000

11

BROMO ACETIC ACID

15.000

--

15.000

12

BROMO ACETYL BROMIDE

5.000

--

5.000

13

DIBROMO ACETIC ACID

5.000

--

5.000

 

BY PRODUCTS FROM EXISTING PRODUCTION

 

 

 

14

CETYL BROMIDE

6.314

--

6.314

15

PHOSPHORIC ACID

0.472

--

0.472

16

SULPHURIC ACID

22.180

--

22.180

17

PHOSPHOROUS ACID

4.140

--

4.140

18

LIQUOR AMMONIA

4.380

--

4.380

19

ANILINE

1.020

--

1.020

20

SODIUM BROMIDE

21.230

--

21.230

 

2.    Proposed Products (Additional) with Production Capacity

Sr

 

Product

 

Production capacity in MT/month

Existing

Proposed

Total

       1.             

(Z)-2-(Tert-methoxy carbonyl-Methoxyimino)-2-(2-aminothiazol-4-yl) acetic acid (MICA acid)

Nil

2.000

2.000

       2.             

S-2-benzothiazolyl(Z)-2-(2-aminothiazol-4-yl)-2-methoxy-carbonyl-methio acetate (MICA ester)

Nil

4.000

4.000

       3.             

Cefotaxime  Acid             

Nil

4.000

4.000

       4.             

Ceftriaxone Sodium

Nil

2.000

2.000

       5.             

Chloramphenicol  succinate       

Nil

5.000

5.000

       6.             

6-hydroxy-3, 4-dihydro carbostyril

Nil

2.000

2.000

       7.             

Dihydroxy ethyl ester

Nil

2.000

2.000

       8.             

2, 3 Dichlorobenzoyl cyanide

Nil

2.000

2.000

       9.             

L -proline benzyl ester hydrochloride

Nil

2.000

2.000

     10.           

4-hydroxy-2-methyl-N-(5-methyl-2-thiozolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide

Nil

2.000

2.000

     11.           

5-Amino salicylic acid

Nil

5.000

5.000

     12.           

Dibenzo [b,f] [1,4] thiazepine-(10H)-11-one

Nil

2.000

2.000

     13.           

Valproic acid

Nil

5.000

5.000

     14.           

1-(2-amino-1-(4-methoxy phenyl) ethyl cyclohexanol

Nil

2.000

2.000

     15.           

Chlorhexidine base (a)

Nil

10.000

10.000

Chlorhexidine base / and its salts (b)

Nil

     16.           

Sodium 2-ethyl hexanoate

Nil

25.000

25.000

     17.           

7-[2-(2-amino-4-thiazolyl)-2(methylcarboxymethonylimino) acetamido]-3-vinyl-3-cephem-4-carboxyllic acid methyl ester

Nil

5 MT of any individual product, and 15 MT combined production of all 11 products

15.000

     18.           

7-[2-(2-amino-4-thiazolyl)-2(methylcarboxymethonylimino) acetamido]-3-vinyl-4-carboxyllic acid trihydrate

Nil

     19.           

2,4-difluoro-2-(1H-4-amino-1,2,4-triazol-1-yl) acetophenone

Nil

     20.           

2,4-difluoro-2-(1H-1,2,4-triazol-1-yl) acetophenone

Nil

     21.           

4-(3,4 dichlorophenyl)-3,4-dihydronaphthalene-1-(2H)-one

Nil

     22.           

5 methylpyrazine 2- carboxyllic acid

Nil

     23.           

2-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl) acetonitrile (b)

Nil

2-(1-hydroxycyclohexyl)-  2-(4-methoxyphenyl) acetonitrile (a)

Nil

     24.           

2-amino-3-cyano-5-methylthiophene

Nil

     25.           

3-(2-chloro-6-fluoro phenyl)-5-methylisoxazole-4-carbonylchloride - FCMIC

Nil

     26.           

3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carbonylchloride - DCMIC

Nil

     27.           

3-(2-chlorophenyl)-5-methylisoxazole-4-carbonylchloride - CMIC

Nil

20.000

20.000

     28.           

HBr aqueous, 48%

Nil

25 MT combined

25.000

     29.           

HBr in acetic acid

Nil

     30.           

Pyridine

Nil

25.000

25.000

       

        3. By Products                                                                                                   

Sr

 

Product

 

Production capacity in MT/month

Existing

Proposed

Total

 

By products from New products

 

 

 

     31.           

sodium sulphate

Nil

36.364

36.364

     32.           

HCl acid

Nil

0.800

0.800

     33.           

phosphorous oxychloride

Nil

1.490

1.490

     34.           

cuprous chloride

Nil

1.143

1.143

     35.           

2 - mercapto benzothiazole

Nil

1.863

1.863

 

 TOTAL PRODUCTION (Existing + Proposed Additional)

344.736

202.660

547.396

 

Cadila Pharmaceuticals to expand its bulk drugs unit at Ankleshwar


Cadila Pharmaceuticals to expand its bulk drugs unit at Ankleshwar in Bharuch district of Gujarat at its existing premises with an investment of Rs. 480 million. The expansion details of the new unit are as follows.

Sl.No.

Name of Products

Type

Production Capacity

(Kg/Month)

Existing    

Proposed

1.

Erythromycin Stearate/Estolate I.P.

Bulk Drug

1869

-

2.

Erythromycin Ethyl succinate USP

Bulk Drug

290

-

3.

Nembutyle Ester

Bulk Drug

1875

-

4.

Pentothal Acid

- do -

540

-

5.

Pentothal sodium

- do -

500

-

         

6.

Megaldrate

- do -

3300

-

7.

Clarithromycin

- do -

333

-

8.

Terazosin

- do -

2

-

9.

Amlodipine Besylate

Bulk Drug & Intermediate

-

2400

10.

Carvedilol

Bulk Drug & Intermediate

-

700

11.

Celecoxib

- do -

-

4400

12.

Chlorhexidine Acetate

- do -

-

1730

13.

Chlorhexidine  Base

- do -

-

12000

14.

Chlorhexidine Gluconate

- do -

-

156000

15.

Chlorhexidine  HCL

- do -

-

4950

16.

Cilostazone

- do -

-

1080

17.

Desloratadine

- do -

-

290

18.

Doxazocin Mesylate

- do -

-

200

19.

Fluconazole

- do -

-

200

20.

Fluoxetine HCI

- do -

-

1310

21.

Glibenclamide

- do -

-

2400

22.

Lacidipine

- do -

-

30

23.

Losartan Potassium

- do -

-

1000

24.

Loratadine

- do -

-

900

25.

Meloxicam

- do -

-

58

26.

Nebivolol

- do -

-

72

27.

Olanzapine

- do -

-

130

28.

Ondensatron

- do -

-

100

29.

Pioglitazone

- do -

-

1000

30

Rabeprazole

- do -

-

300

31.

Setraline HCI

- do -

-

200

32.

Sildenafil Citrate

- do -

-

300

33.

Venlafaxine

- do -

-

750

34.

VF-2 HCI

- do -

-

3000

35.

Zolpidem

- do -

-

76

36.

Torasemide

- do -

-

100

37.

Aripiprazole

- do -

-

100

38.

Atorvastatine

- do -

-

100

39.

Ezetimibe

- do -

-

100

40.

Fexofenadine

- do -

-

673

41.

Irbesartan

- do -

-

500

42.

Itopride HCI

- do -

-

508

43.

Olmesartan

- do -

-

80

44.

Rabemipide

- do -

-

80

45.

Nateglinide(CTD)

- do -

-

665

46.

Ropinirole

- do -

-

100

47.

Rupatidine

- do -

-

160

48.

Telmisartan

- do -

-

100

49.

Valsartan

- do -

-

200

50.

Etambutol HCI

- do -

-

1000

Total

8709

2,00,042

 

KDAC Chem to expand its bulk drug unit at Nandesari in Gujarat


KDAC Chem to expand its bulk drug unit at Nandesari in Vadodara district in Gujarat with an investment of Rs. 45 million. The new bulk drug unit expansion details are as follows.

S.N.

Products? name

Existing Products (MTPM)

Proposed New Products (MTPM)

1

Campholenic Aldehyde

10.0

-

2

Sandenol Capcore

0.5

-

3

Sandenol

0.5

-

4

Woodysol (By product)

1.0

-

5

Sodium Acetate Solution 30 % (By product)

30.0

-

6

Syrene Oxide

-

100

7

Phenyl Ethyl Alcohol

-

100

8

Phenyl Ethyl Methyl Ether

-

10

9

2 Phenyl Ethyl Acetata

-

50

10

Allyl ISA Thio Cyanate

-

5

11

Ethyl Vaniline

-

10

12

Vaniline

-

10

 

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