Bulk Drug Manufacturing

Shilpa Medicare to expand bulk drug unit at Raichur

Details: Category: Bulk Drug Manufacturing

Shilpa Medicare to expand bulk drug unit at Raichur in Karnataka with an investment of Rs. 218 million. The capacity of the project, after expansion will be 126.75 TPA. The expansion details of the new unit are as follows.

s. No.	Name of Products	Capacity (MTA)
1	Ambroxol HCI	47
2	Anastrozole	0.1
3	Bicalutamide	0.5
4	Carboplatin	0.35
5	Cisplatin	0.1
6	Coenzyme Q-10	18
7	Docetaxel	0.1
8	Gemcitabine HCI	0.3
9	Irinotecan HCI Trihydrate	0.1
10	Oxaliplatin	0.05
11	Paclitaxel	0.1
12	Temozolomide	0.1
13	3a, 7B-Dihydroxy Cholanic Acid	60
Total		126.8

Arihantanam Organics setting up a bulk drug unit at Sarigam

Details: Category: Bulk Drug Manufacturing

Arihantanam Organics setting up a bulk drug unit at Sarigam in Valsad district of Gujarat with an investment of Rs. 5.0 million. The following products are herbal extracts and will be manufactured from natural sources.

Product No.	Products	Quantity in MTM
1	Quinine Sulphate
2	Quinine Hydro Chloride	10.00
3	Quinine di Hydro Chloride
4	Quinine bi Sulphate
5	Arteether
6	Artemether	0.5
7	Artesunate
8	Artemisinine

SPC Lifescience to expand bulk drug unit at Ankleshwar

Details: Category: Bulk Drug Manufacturing

SPC Lifescience to expand bulk drug unit at Ankleshwar in Bharuch district of Gujarat with an investment of Rs. 21.3 million. The expansion details of the new unit are as follows.

S. No	Products	Existing Capacity (MTM)	Proposed Increase (MTM)	After Expansion (MTM)
Existing Products
1.	Dimethyl Amino Ethyl Chloride Hydrochloride OR Diethyl Amino Ethyl Chloride Hydrochloride OR Bis-Chloro Ethyl Amino Hydrochloride	20.0 20.0 20.0	0.0 0.0 0.0	20.0 20.0 20.0
2.	Mannich Hydrochloride	15.0	0.0	15.0
3.	Dimethyl Amino Propyl Chloride Hydrochloride solution	20.0	0.0	20.0
4.	Chloro Hexane-one	10.0	0.0	10.0
Additional New Products
1.	4-(4-Fluorophenyl)-3-hydroxymethyl-1 methyl piperidine (BISCARBINOL) OR 4 Aryl-3-hydroxymethyl Piperidine	0.0	5.0	5.0
2.	2 n - Butyl Benzofuran	0.0	3.0	3.0
3.	2 n - Butyl 3 ( 4 - Hydroxy Benzoyl ) Benzofuran	0.0	2.5	2.5
4.	2 n - Butyl 3 ( 3, 5 DI Iodo -4 - Hydroxy Benzoyl ) Benzofuran	0.0	4.0	4.0
5.	3 Chloropropiophenone	0.0	10.0	10.0
6.	2 - ( 2 Chloroethoxy ) Ethanol	0.0	3.0	3.0
7.	2 ( 2 Chloroethoxy ) Ethyl Acetate	0.0	3.0	3.0
	Total	65.0	30.5	95.5
By Products
1.	KBr Solution (From Butyl Benzofuran)	0.0	25.0	25.0
2.	Acetic acid (From Butyl Benzofuran)	0.0	3.5	3.5
3.	Aq. AlCl3 (From Butyl Hydroxy Benzoyl Benzofuran, 3- Chloropropiophenone )	0.0	117.0	117.0
4.	Aqueous Sodium Iodide	0.0	19.0	19.0
	Total	0.0	=SUM(ABOVE) 164.5	164.5

The Existing Gas Consumption is 350 NM3/Day which will increase to 1250 NM3/Day. The existing unit has one LDO based D. G. Set of 62.5 KVA and one more of 250 KVA based on natural gas is proposed. The total Power requirement of 500 KVA is met through DGVCL (State Electricity Board) supply.

RPG Life Science to modernize its bulk drug unit at Ankleshwar

Details: Category: Bulk Drug Manufacturing

RPG Life Science to modernize its bulk drug unit at Ankleshwar in Bharuch district of Gujarat with an investment of Rs. 20 million. The project also involves expanding the present production capacity of Bulk Drugs from 83.3 kg/ month (1.0 TPA) to 150.0 kg/m (1.8 MTA) as per the following details-

S.No.	Name of the product	Existing	Proposed	Total
1	Cyclosporine	64.2	31.8	96.0
2	Mycophenolate Mofetil	42.5	47.5	90.0
3	Daunomycin Hydrochloride	33.3	Nil	33.0
4	Daxorubicin Hydrochloride	20.0	Nil	20.0
5	Epirubicin Hydrochloride	6.0	Nil	6.0
6	Lovastatin	70.8	Nil	70.8
7	Pravastatine	69.0	Nil	69.0
8	Orlistat	49.5	Nil	49.5
9	Hyluronic Acid	Nil	52.8	52.8
10	Methyl Cobalamine	Nil	25.0	25.0
11	Idarubicin	Nil	6.0	6.0
12	Pirarubicin	Nil	6.0	6.0
13	Tachrolimus	Nil	108.0	108.0
14	Sirolimus (Rapamycin)	Nil	108.0	108.0
15	11-Alpha hydroxy Canrenon	Nil	134.4	134.0
	Total	83.3	66.7	150.0