Prudence Pharma Chem to set up bulk drug unit at Ankleshwar in Bharuch district of Gujarat with an investment of Rs. 11.7 million. . It is proposed to stop the existing products and to manufacture various other bulk drugs and intermediates with installed capacity of 10 MTPM within the same premises. Besides 12 MTPM of Bulk Intermediates and by-products will be manufactured.
Details of products along with their production capacity are given below:
Sr. No. | Name of Products | Chemical Name of Product | Capacity, MT/Month |
Group A | |||
A-1. | Losarton Potassium (LSR) | (2-n-butyl-4-chloro-5-hydroxy-methyl-1-[(2`-(1H-tetrazol-5-yl potassium OR OR [1- {2`- (2H-tetrazol-5-yl) biphenyl -4-yl}methyl]-2-butyl-4-chloro-1H-imidazol -5-yl) methanol potassium | 3.0 |
A-2. | Metaxalone (MX) | 5-[(3,5-dimethylphenoxy)methyl]oxazolidin-2-one OR 5-(3,5-Dimethyl Phenoxy methyl)-2-oxazolidinone | |
A-3. | Amlodipine Besylate (AMB) | 3-Ethyl 5-methyl (4RS)-2-[(2-aminoethoxy) methyl]-4-(2-chlorophenyl)-6-methyl-1, 4-dihydropyridine-3, 5-dicarboxylate benzenesulphonate. | |
Group B | |||
B-1. | Glibenclamide (GLB) | 1-[{4-(2-[(5-Chloro-2-ethoxybenzoyl) amino] ethyl) phenyl} sulphonyl]-3-cyclohexylurea. | 7.0 |
B-2. | Niclosamide | 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide | |
Total Capacity (Group A + B) | 10.0 |
List of Intermediate Products
Sr. No. | Production Stage | Chemical Name of Intermediate product | Kg/Kg of Finished product | Capacity, MT/Month |
Group A | ||||
A-1 | Stage 1 (LSR -1) | 3-Butyl-4-chloro 5-methyl hydroxy N-(4-methyl 2-cyno biphenyl) imidazole | 1.25 | 3.75 |
Stage 2 (LSR -2) | 1.00 | 3.00 | ||
A-2 | Stage -1 (MX- 1) | 2-[(3,5-dimethylphenoxy)methyl]oxirane | 2.32 | 6.96 |
Stage -2 (MX- 2) | 1-amino-2-(3,5-dimethylphenoxy)ethanol | 1.67 | 5.01 | |
A-3 | Stage -1 (AMB- 1) | Hydroxy ethyl Phthlamide [HEP ] | 1.35 | 4.05 |
Stage -2 (AMB- 2) | Methy 3 Amino Crotonate [MAC] | 2.00 | 6.00 | |
Stage -3 (AMB- 3) | Ethyl -4-(2-Phthlamide) ethyl aceto acetate. [PHEMA] & Phthloyal Amlodipine | 1.50 | 4.50 | |
Stage -4 (AMB- 4) | 1.00 | 3.00 | ||
B-4 | Stage -2 (GLB 2) | Sulphonamide | 0.72 | 5.04 |
| Maximum Capacity | Group A |
| 6.96 |
Group B |
| 5.04 | ||
|
| Total Capacity (Group A + B) |
| 12.00 |
* The unit may sale intermediate products at any stage as stated above from the manufacturing of each product.
* The maximum production capacity of intermediate products will not exceed 12.00 MT/Month
List of By-Products
Sr. No. | Source | Name Of The Byproducts | Capacity, MT/Month |
GROUP A | |||
1. | APCE for Metaxalone (A -2 ) | 150.00 | |
GROUP - B | |||
1. | APCE for Glibenclamide (A -2 ) | 6.70 | |
9.80 | |||
2. | APCE for Niclosamide (A -2 ) | 3.00 | |
4.40
| |||
|
|
|
|
150.00 | |||
6.70 | |||
9.80 |
|
11,950 ₹ | 4950 ₹ | 4950 ₹ | 4950 ₹ | 3950 ₹ |
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