Bulk Drug Manufacturing

Apithecary Pharma to set up bulk drug unit at Chandampeth village in Medak

Details: Category: Bulk Drug Manufacturing

Apithecary Pharma to set up bulk drug unit at Chandampeth village in Shankarampet mandal in Medak district of Andhra Pradesh. It is proposed to expand the project with 18 new bulk drugs and drop all the permitted intermediates. These products will be manufactured on campaign basis i.e any four bulk drugs or corresponding quantities of their intermediates out of 18 products will be manufactured at a time with an overall maximum quantity of 210 TPA.

S. No.	Product	Capacity TPA
Proposed Bulk Drugs - Campaign products
1	Abacavir Sulfate	24.0
2	Clopidogrel Hydrogen sulfate	24.0
3	Doxazosin Mesylate	1.2
4	Efavirenz	12.0
5	Entacapone	36.0
6	Fexofenadine Hydrochloride	48.0
7	Fluconazole	30.0
8	Lamivudine	12.0
9	Lamotrigine	24.0
10	Lansoprazole	12.0
11	Mebeverine Hydrochloride	54.0
12	Omeprazole	24.0
13	Ropinirole Hydrochloride	1.2
14	Tamsulosin Hydrochloride	1.2
15	Terbinafine Hydrochloride	36.0
16	Zidovudine	48.0
17	Sertraline Hydrochloride	42.0
18	Tramadol Hydrochloride	60.0
Permitted Intermediates (CFE permitted Products) ? Dropped
1	3-Methyl-4[[((2,2,2-Trifluoro Ethoxy)-2-Phridiny) Methyl] thio]-1 H-Benzimidazole	7.2
2	DCPCN ? Amine	72.0
3	2(2,4, Difluor Phenyl)-1-(1H-1,2,4-Triazole-1 YL)-2,3 Epoxy Propane Methane) Sulphonate	21.6
4	2 Dimethyl Amino Methyl Cyclo Hexanone HCl	6
By-product
1	Pyridine Hydrochloride	88.8
2	Aluminum Hydroxide gel	1300.2
3	Spent Sulfuric Acid	206.83
4	Tritanol	84.77
5	Hydrogen Bromide Solution	45

Astrica Laboratories Pvt. Ltd to set up bulk drug and intermediates plant at Chengunta mandal

Details: Category: Bulk Drug Manufacturing

Astrica Laboratories Pvt. Ltd to set up bulk drug and intermediates plant at village Ananthsagar in Chengunta mandal in Medak district of Andhra Pradesh. It is proposed to manufacture 15 new bulk drugs along with their intermediates on campaign basis i.e. any 4 products at a time. The total project cost is estimated at Rs. 78 million.

The details of various products and their production capacities are as given below:

S. No.	Products	Capacity TPA
Proposed Bulk Drugs ? Campaign products
1.	Terbinafine Hydrochloride	60
2.	Clopidogrel Hydrogen Bisulfate	60
3.	Moxifloxacin Hydrochloride Monohydrate	60
4.	Darifenacin	36
5.	Olmesartan	12
6.	Montelukast Sodium	12
7.	Zidovudine	60
8.	Ramipril	12
9.	Duloxetine Hydrochloride	24
10.	Amlodipine Besylate	36
11.	Ketorolac Tromethamine	12
12.	Pantoprazole Sodium	60
13.	Omeprazole	60
14.	Lansoprazole	48
15.	Rabeprazole Sodium	36
By-products
1	Alphapinene	11.04
2	Tritanol	105.9
3	Spent HCl	36.4
4	Spent Sulfuric acid (22.5%)	773.6

* Any four out of above fifteen products will be manufactured at a time.

Arvee Chem Pharma to set up bulk drug plant at Toremavu in Nanjangud i

Details: Category: Bulk Drug Manufacturing

Arvee Chem Pharma to set up bulk drug plant at Toremavu in Nanjangud in Mysore district of Karnataka. The expansion details of the new unit are as follows.

S.N.	Products	Quantity (MTPA)
1	Azacyclonol Base	60
2	Di Benzo Suberone	60
3	ISO Nipecotic Acid	50
4	ISO Nipecotic Acid Ethyl Ester (INEE)	20

Bajaj Healthcare to expand bulk drug plant at Salvi in Gothada

Details: Category: Bulk Drug Manufacturing

Bajaj Healthcare to expand bulk drug plant at Salvi in Gothada in Vadodara taluk in Gujarat. The new plant will manufacture the following products after expansion.

Sr. No.	PRODUCTS	Quantity (MT/Month)
Sr. No.	PRODUCTS	Existing	Total After Proposed Expansion
1	2-Mercapto Benzinidazole	5	-*
2	o-Phenylene Diamine	2	-*
3	Chlorzoxazone	2	-*
4	2-ARY-2-H-Benzotriazone	0.5	-*
5	-Lactone of L-Gluconic acid (Ascorbic Acid)	25	200
6	Valeryl Chloride	0.5	-*
7	Methyl ortho Valerate	0.5	-*
8	Methyldopa (usp-24)	3	-*
9	Chlorohexexidine Base	3	50
10	Chlorohexidin Digluconate Solution (20 %)	20	200
11	Chlorohexidin Dihydrochloride	1	10
12	Chlorohexidin Diacetate	1	5
13	Diprophylline	-	5
14	Choline Bitartrate	-	50
15	Choline Dihydrogen Citrate	-	10
16	Calcium Phosphoryl Choline Chloride	-	10
17	Imino Stilbene Carboxyl Ammonium Chloride	-	30
18	Bromo Ethyl Theophylline	-	5
19	Sodium Saccharine	-	250
20	Insoluble Saccharine	-	50
21	Calcium Ascorbate	-	2
22	Calcium Saccharine	-	5
23	Ferrous Ascorbate	-	10
24	L- Lysine mono HCL USP	-	50
25	Calcium Citrate USP	-	20
26	Calcium Citrate Malate	-	20
27	Acefylline Piperazine	-	5
28	L- Glutamic Acid USSRP	-	5
29	Choline Theophyllinate BP	-	5
Total		63.5	997